School of Engineering \ Biomedical Engineering
Course Credit
ECTS Credit
Course Type
Instructional Language
Programs that can take the course
Department of Biomedical Engineering Department
This course covers key discoveries in the history of cell and molecular biology along with the following topics: protein transport to membranes and organelles; protein modification, folding, and quality control in the ER; vesicular trafficking, secretion, and endocytosis; protein transport to mitochondria, chloroplasts, peroxisomes, and the nucleus; cell imaging (microscopy); purification of cellular organelles; protein purification and analysis, proteomics; structural organization of eukaryotic chromosomes and chromosomal mutations; eukaryotic gene structure, chromosomal organization of genes, non-coding DNA, transposable DNA elements, organelle DNA, molecular genetic techniques, gene mutations; cell culture, cell birth, and lineage maintenance; stem cells and stem cell technology; cellular aging, cell death, and the regulation of cell death; and cancer.
Textbook and / or References
• Moleküler Hücre Biyolojisi –Lodish . 6. baskıdan çeviri, Palme Yayıncılık
• Genetik Kavramlar- William S. Klug, Michael R. Cummings, Charlotte A. Spencer- 8. baskıdan çeviri, Palme Yayıncılık, 2011
The aim of BMM 202 course is provide students with up-to-date knowledge at a foundational level on topics essential for Biomedical Engineering education, such as molecular biology, cell biology, genetics, physiology, tissue engineering, pharmacology and toxicology, biotechnology, genetic engineering, nanomedicine, biosensors, bioinformatics, drug design, and enzymology. Additionally, it aims to offer insights into how they can apply this knowledge in their professional careers.
1. Gaining up-to-date knowledge that forms a foundation for more specific fields such as molecular biology, cell biology, physiology, tissue engineering, pharmacology, toxicology, biotechnology, genetic engineering, nanomedicine, biosensors, bioinformatics, drug design, and enzymology.
2. Acquiring insights into where this knowledge can be applied in professional life.
3. Gaining experience in accessing information, conducting literature searches, and citing references.
Week 1: Introduction to the course, important steps in the history of molecular biology
Week 2: Transport of proteins to membranes and organelles
Week 3: Vesicular traffic, secretion and endocytosis
Week 4: Imaging of cells (microscope), purification of cell organelles
Week 5: Purification and study of proteins, Proteomics
Week 6: Structural organization of eukaryotic chromosomes and chromosomal mutations
Week 7: Eukaryotic gene structure, chromosomal organization of genes and non-coding DNA, transposable DNA elements, organelle DNA
Week 8: Gene mutations
Week 9: Cell culture, birth of the cell, continuation of the cell line
Week 10: Stem cell and stem cell technology
Week 11: Cellular aging, cell death and regulation of cell death
Week 12: Cancer
Tentative Assesment Methods
• Midterms 35 %
• Final 40 %
• Quizzes 15 %
• Homeworks 10 %
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