BMM446

Thermodynamics of Biomolecular Systems

Faculty \ Department
School of Engineering \ Biomedical Engineering
Course Credit
ECTS Credit
Course Type
Instructional Language
3
6
Elective
English
Prerequisites
-
Programs that can take the course
Biomedical Engineering
Course Description
BMM 446 involves the laws of thermodynamics and its applicaitons. In this regard, the following will be conveyed: state functions, work and energy, enthalpy, entropy, differences in biological systems, and connection between information and entropy.
Textbook and / or References
• Haynie, D., Biological Thermodynamics (2nd ed.), 2008, Cambridge University Press, Cambridge, UK
• Blundell, K.M., Blundell, S., Concepts in Thermal Physics, (2nd ed.), 2009, Oxfor University Press, Oxford, UK
Course Objectives
The course aims to convey the fact that laws of thermodynamics underlie the working mechanisms of biological systems, understanding thermodynamic processes behind biological systems to realize how the application of thermodynamics give rise to addressing a range of problems in biological world
Course Outcomes
1. Realising the power of thermodynamics to unveil natural laws
2. Understanding and calculating work and energy balances in biological systems
3. Ability to recognize the differences between biological and non-biological system in terms of thermodynamics
Tentative Course Plan
Week 1 History of thermodynamics and its definition
Week 2 Fundamental concepts in thermodynamics
Week 3 Heat and temperature
Week 4 Zeroth law and function of state
Week 5 First law and the concept of work
Week 6 Enthalpy
Week 7 Calorimetry
Week 8 Second law
Week 9 Entropy ve Maxwell's demon
Week 10 Gibbs and Shannon entropy
Week 11 Chemical potential
Week 12 Energy, information and life
Tentative Assesment Methods
Activities Number Weight (%)
Course Attendance/Participation - -
Laboratory - -
Application - -
Homework 1 20%
Project - -
Presentation - -
Field Work - -
Internship - -
Course Boards - -
Quiz - -
Midterm Exam 1 35%
Final Exam 1 45%
Total 100%

Tentative ECTS-Workload Table
Activities Number/Weeks Duration (Hours) Workload
Course Hours (first 6 weeks) 6 4 24
Course Hours (last 6 weeks) 6 3 18
Laboratory - - -
Application - - -
Homework 1 24 24
Project - - -
Presentation - - -
Field Work - - -
Internship - - -
Course Boards - - -
Preparation for Quiz - - -
Preparation for Midterm Exam 1 26 26
Final Exam 1 2 2
Preparation for Final Exam 1 36 36
Study Hours Out of Class (preliminary work, reinforcement, etc.) 12 3 36
Total Workload 166
Total Workload / 30 166 / 30
ECTS Credits of the Course 6
Program Outcome **
1 2 3 4 5 6 7 8 9 10 11
Course Outcome
1 A A
2 D B A A A
3 A B A A A