TIP101

School of Medicine \ Medicine

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9

Compulsory

Turkish

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Bachelor's and Master's Degrees

In this course, it explains the structures and properties of basic organic molecules. Identifies functional chemical groups found in biomolecules Counts which chemical bonds are in biomolecules. Knows the properties of water molecules and defines the concepts of solubility, solvent and solute. Describes the molecular structure of proteins and their building blocks, amino acids. Describes the basic structures of carbohydrates, lipids and nucleotides Explains the structural properties of enzymes, how they work and their catalytic mechanisms. It lists the historical development of medicine and medical practices in ancient civilizations. It explains the birth of post-Hippocratic medicine, medieval medicine and modern medicine. Knows the structure, historical development and recent medical history of health services in Turkey.

"Lehninger Principles of Biochemistry, 8th Edition, D. L. Nelson, M. M. Cox. WH Freeman and Company 2021.
Molecular Biology of the Cell, 6th Edition, B. Alberts, A. Johnson, J. Lewis, D. Morgan, M. Raff, K. Roberts, P. Walter. Garland Science, Taylor & Francis 2015.
Introduction to General, Organic and Biochemistry, 10th edition, M. Hein, S. Pattison, S. Arena, John Wiley & Sons Inc. 2012.
Medicine, An Illustrated History. Lyons, A. , Petrucelli, R. New York, Abrams. 1987.
A History of Medicine. Castiglioni, A. New York, Knopf. 1947.
Tıp Tarihi. Bayat, A. H. İstanbul, Merkezefendi Geleneksel Tıp Tarihi. 2010. "

1. The aim of this course is to teach the history of medicine and the molecular and cellular information that forms the basis of medical education.

1. Explain the structures and properties of basic organic molecules
2. Identify the functional chemical groups found in biomolecules
3. Counts which chemical bonds are in biomolecules
4. Knows the properties of water molecules and defines the concepts of solubility, solvent and solute. defines
5. Describes the molecular structure of proteins and their building blocks, amino acids.
6. Describe the basic structures of carbohydrates, lipids and nucleotides
7. Explains the structural properties of enzymes, how they work and their catalytic mechanisms.
8. Counts the historical development of medicine and medical practices in ancient civilizations.
9. Explains the birth of post-Hippocratic medicine, medieval medicine and modern medicine
10. The structure of health services in Turkey, its historical development and recent medical history knows
11. Makes the necessary calculations to prepare the solution
12. Prepare buffer solution using balance and pH meter
13. Measures using a spectrophotometer device
14. Hand washing and mask-wearing
15. Gains the ability to remove waste
16. Gains the ability to put on and take off gloves
17. Gains the ability to stop bleeding
18. Gains the ability to transport patients
19. Make a presentation on a selected topic in the field of medical history

Week 1: Introduction to faculty administrators: Regulations, administrative procedures and exams - Introduction of the first-year curriculum and TOBB ETU MF Morphology building - Rules to be followed in laboratories and preparation of laboratory report - Determination of learning trends and learning contract - Concept of medicine and ethics - Evolution of biomolecules - Introduction to biochemistry - Functional groups, chemical bonds and weak interactions in biomolecules - Role in water and biological systems - Solutions, solution preparation and concentration calculations - Introduction to organic chemistry - Common Courses
Week 2: Stereochemistry - An overview of the historical development of medicine and the practice of medicine in early civilizations - The Ability to Wash Hands and Wear Masks - Lipids: their structure, properties and functions - Buffers and buffering mechanism - Organic chemistry: Nomenclature, stereochemistry, alkanes, alkenes, alkynes, alkyl halides -
Biochemistry Lab - Common Courses
Week 3: Carbohydrates: Structure, properties and functions - Organic chemistry: Alcohols, phenols, ethers, aldehydes and ketones, carboxylic acids - Structure and Historical development of health services in Turkey - Science and scientific research - Electrochemistry - Spectrophotometry: Principles and areas of use - Nucleotides: Structure, properties and functions - History of clinical and preventive medicine - History of Surgery - Amino acids: Structure, properties and functions - Carboxylic acids - History of diagnosis and treatment - Ability to Wash Hands and Wear Masks Evaluation - Biochemistry Lab - Common Courses
Week 4: Ability to Wear and Remove Gloves - Waste management - Information literacy and evidence-based medicine - History of public health and infectious diseases - Proteins: Their structure, properties and functions - Reliable information and publication ethics - History of clinical research - Ability to Wear and Remove Gloves - Proteins: Isolation and structure analysis - Common Courses
Week 5: Enzymes and enzymatic catalysis - Amines - Ability to Put On and Take Off Gloves - Evaluation - Enzyme kinetics - Aromaticity and benzene - Control of enzyme activity - Vitamins and coenzymes - Nobel Prize - Biochemistry Lab - Joint Courses - Biochemistry Lab Compensation
Week 6: Biochemistry Lab Exam - Theoretical Exam - Common Courses
Week 7: Glycogen degradation and synthesis - Physiology Lab: Introduction to the physiology laboratory - Biophysics Lab: Factors affecting the electrical potential of the cell membrane - Biochemistry Lab: Electron transport chain - Physiology Lab: Use of formulas in physiological signals, evaluation of nomograms and graphs - Common Courses
Week 8: Genetic control mechanisms – Prokaryotes - Opening a syringe, drawing medication from an ampoule, intramuscular injection - Practice - Fatty acid synthesis - Comparison of two independent groups – Parametric - Lipid synthesis - Electrical potentials of the membrane in the neuron model
Week 9: Electrical excitability and action potential in the neuron model - Physiology Lab: Osmotic pressure: Elodea experiments - Biophysics Lab: Action potential and nerve conduction velocity - Common Courses, Theoretical synthesis of amino acids and other nitrogenous compounds
Week 10: Mendelian principles - Fundamentals of bioelectric measurement - Mendelian genetics in medicine - Biophysics: Discussion - Biophysics: Discussion - Comparison of two independent groups – Non-parametric - Opening a syringe, drawing medication from an ampoule, intramuscular injection - Evaluation
Week 11: Models of inheritance - Nucleotide synthesis - Non-Mendelian inheritance - Biochemistry: Discussion - Other electrically excitable cells – Muscle - Receptor cells - Article reading - Physiology Lab: Osmotic pressure: Blood experiments - Common Courses
Week 12: Physiology Lab: Make-up - Biochemistry Lab: Make-up - Biophysics Lab: Make-up - TIP103 End-of-Block Theoretical Exam - TIP103 End-of-Block Practical Exam - Biophysics - TIP103 End-of-Block Practical Exam - Physiology - Common Courses

• Theoretical exam: 80 %
• Laboratory: 16 %
• Application: 4 %