TIP103

School of Medicine \ Medicine

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9

Compulsory

Turkish

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Medicine Bachelor's Degree Program

In Medical Biochemistry courses, metabolic pathways related to the breakdown of fats and proteins, electron transport system, modified biosynthetic metabolic pathways and biochemistry of some organelles are explained. In the Medical Biology department, DNA technology and methods preparation methods, non-Mendelian inheritance, cell theory and cancer biology can be discussed. Histological features of organelles in the cell structure and histological techniques are given. Project studies carried out within the scope of good practices in medicine courses, medical waste management, decontamination of the materials contained, pulse and blood pressure measurements, presentation methods are given. Basic homeostatic mechanisms, functional properties of the cell membrane, potential potentials and substance transport are discussed.

"Lehninger Principles of Biochemistry, 8th Edition, D. L. Nelson, M. M. Cox. WH Freeman
and Company 2021.
Molecular Biology of the Cell, 6th Edition, B. Alberts, A. Johnson, J. Lewis, D. Morgan,
M. Raff, K. Roberts, P. Walter. Garland Science, Taylor & Francis 2015.
Berne & Levy Physiology, 6th Updated Edition, with Student Consult Online Access,
Koeppen BM, Stanton BA, 2009.
Vander's Human Physiology: The Mechanisms of Body Function. , 15th Ed. Eric W,
Hershel R. 2019.
Sağlık Bilimlerinde Bilimsel Araştırma Yöntemlerine Giriş. Burak Mete, Hakan
Demirhindi. Akademisyen Kitabevi, 2022. "

The purpose of this course is to teach the basic metabolic information and biophysical principles of medical education.

1. Glycolysis, TCA subject, oxidation of fatty acids and metabolism of amino acids show the steps, parts and control mechanisms of the pathways.
2. Distributes why ammonia is toxic and describes how the product works
3. How RNA therapy and genetic information accumulation emerged
4. Folds the processes of transcription and protein synthesis (translation) into steps
5. Acquires basic biophysical information (units and measurements, cellular models).
6. Describes the functional properties of the cell membrane and the processes of transport of molecules through the membrane
7. Mobile adaptability in neurons and muscles, open action potential
8. Basic tests used in statistical evaluations (single ratio test, parametric) and nonparametric independent two-group comparison)
9. Use of formulas in physiological signals, how nomograms and graphs are assessment requirements
10. Stored depending on osmotic pressure, using elodea plant and blood records recognized under a microscope
11. Also in a laboratory environment Shows how the electron transport system works via the reduction of methylene blue.

Week 1: THEORETICAL Glycolysis and its control - Genetic information flow and RNA structure - Biophysical units and measurements - What is a hypothesis? Hypothesis testing - READING ARTICLES - Diffusion and osmosis in biological systems - Transcription and mRNA processing - Tricarboxylic acid cycle - Oxidation of fatty acids - Ionic currents and membrane potential - Nobel Prize 1953: Hans Adolf Krebs and Fritz Albert Lipmann,Citric acid cycle Coenzyme A and its importance in intermediary metabolism - Introduction to Physiological Sciences - Body Temperature, Respiratory Rate, Pulse and Arterial Blood PressureMeasurement skills - Common Courses
Week 2: THEORETICAL Non-coding RNAs - Oxidation of amino acids and detoxification of ammonia - Body Temperature, Respiratory Rate, Pulse and Arterial Blood Pressure Measurement Skills - APPLICATION - Genetic Code - P value, Type I and Type II error, Power of WORK - Basic Physiological Mechanisms and Homeostasis - Membrane Potential of Excitable Cell - Body Temperature, Respiratory Rate, Pulse and Arterial Blood Pressure Measurement Skills - EVALUATION - Protein Synthesis - Physiological Signals and Their Evaluation - Basic Electrical Principles - Electrical Model of Cell Membrane - Opening a Syringe, Drawing Drug from Ampoule into Syringe, Intramuscular Injection - BIOCHEMISTRY LAB.: Transamination and Paper Chromatography - Common Courses
Week 3: THEORETICAL Genome Anatomy - Electron transport system and oxidative phosphorylation - Pentose phosphate and glucuronic acid metabolic pathways - Mutation and mutagenesis - One sample t test - Functional properties of the cell membrane and transport in the membrane - Mutation types - Cable theory and conduction in the axon - Gluconeogenesis - Gluconeogenesis - PHYSIOLOGY LAB: Introduction to physiology laboratory - BIOPHYSICS LAB: Factors affecting the cell membrane electrical potential - BIOCHEMISTRY LAB: Electron transport chain - PHYSIOLOGY LAB: Use of formulas in physiological signals, evaluation of nomograms and graphs - Common Courses
Week 4: THEORETICAL Glycogen degradation and synthesis - Genetic control mechanisms–Prokaryotes - Opening the syringe, drawing the drug from the ampoule into the syringe, intramuscular injection - APPLICATION - Synthesis of fatty acids - Independent two-group comparison–Parametric - Synthesis of lipids - Electrical membrane potentials in the neuron model - Electrical Excitability and Action Potential in the Neuron Model - PHYSIOLOGY LAB: Osmotic pressure: Elodea experiments - BIOPHYSICS LAB: Action potential and nerve conduction velocity - Common Courses
Week 5: THEORETICAL Synthesis of amino acids and other nitrogenous compounds - Mendel principles - Fundamentals of bioelectrical measurement - Mendelian Genetics in Medicine - BIOPHYSICS: Discussion - BIOPHYSICS: Discussion - Independent two group comparisons– non Parametric - Syringe Opening, Drawing Drug from Ampoule into Syringe, IntramuscularInjection - EVALUATION - Inheritance patterns - Synthesis of nucleotides - Non-Mendelian Inheritance - BIOCHEMISTRY: Discussion - Other Electrically Excitable Cells-Muscle - Receptor cells - READING ARTICLES - PHYSIOLOGY LAB.: Osmotic pressure: blood experiments - Common Courses
Week 6: THEORETICAL PHYSIOLOGY LAB. REMEDY - BIOCHEMISTRY LAB. REMEDY - BIOPHYSICS LAB. MAKE-UP - MED103 END OF BOARD THEORETICAL EXAM - MED103 END OF BOARD PRACTICAL EXAM - BIOPHYSICS - MED103 END OF BOARD PRACTICAL EXAM - PHYSIOLOGY - Common Courses