TIP104

School of Medicine \ Medicine

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8

Compulsory

Turkish

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Bachelor's and Master's Degrees

Within the scope of the course board, metabolic pathways related to the destruction of fats and proteins, electron transport system, biosynthetic metabolic pathways in cells and the biochemistry of some organelles are explained in Medical Biochemistry courses. In the Medical Biology course, DNA technology and mutation detection methods, non-Mendelian inheritance, cell cycle and cancer biology are discussed. Lectures are given on the histological features of organelles in cell structure and histological techniques. Within the scope of the good practices in medicine course, project work is carried out and training is provided on medical waste management, decontamination of infected material, pulse and blood pressure measurement skills, and presentation skills. Basic homeostatic mechanisms, functional properties of the cell membrane, electrical potentials and substance transport are discussed.

Lehninger Principles of Biochemistry, 8th Edition, D. L. Nelson, M. M. Cox. WH Freeman
and Company 2021.
Molecular Biology of the Cell, 6th Edition, B. Alberts, A. Johnson, J. Lewis, D. Morgan,
M. Raff, K. Roberts, P. Walter. Garland Science, Taylor & Francis 2015.
An Atlas of Histology, S. X. Zhang 1999. DOI: https://doi. org/10. 1007/978-0-387-
21760-4
A Text and Atlas: With Correlated Cell and Molecular Biology,8th Ed. W. Pawlina, M. H.
Ross 2018. ISBN-13: 978-1496383426
Junqueira's Basic Histology, Text and Atlas, 16th Ed. , A. L. Mescher 2021.
Berne & Levy Physiology, 6th Updated Edition, with Student Consult Online Access,
Koeppen BM, Stanton BA. , 2009.

The purpose of this course board is to teach tissue knowledge and biophysical principles that form the basis of medical education and basic public health concepts.

1. Lists the biochemical properties specific to adipose tissue, connective tissue and blood tissue
2. Explains the biochemical properties of different organelles within the cell
3. Lists the post-synthetic modifications of proteins and protein repair mechanisms
4. Explains the importance of protein targeting and turnover
5. Explains different types of genetic disorders (gene irregularities, structural and numerical chromosome anomalies, etc. ) and lists the types of mutations
6. Describes genetic changes in the cancer process
7. Lists DNA and RNA technologies
8. Lists the structural properties of different tissue types (protective/covering and gland epithelium, connective tissue)
9. Explains the processes of transcription and protein synthesis (translation) in steps
10. Explains the concepts of basic biophysics (analysis of physiological systems, basic principles of imaging, flexibility in biological tissues) and radiation biophysics
11. Has basic public health information (basic concepts in health, community recognition, risk groups, control programs, health policy and organization, international health organizations)

Week 1: THEORETICAL Endoplasmic reticulum, Golgi, peroxisomes and lysosomes Biochemistry - Protective (covering) epithelium - Analysis of physiological systems - Nobel Prize 2004; Aaron Ciechanover, Avram Hershko, Irwin Rose Ubiquitin-mediated protein degradation - Post-synthetic modifications of proteins - Structural and numerical chromosome abnormalities - READING ARTICLES - ETHICS AND BIOSTATISTICS COURSE - Sex Chromosome abnormalities - Analysis of physiological systems - Course introduction and basic concepts in health - Traces in public health - Direction of proteins, protein turnover and its importance Intravenous Intervention - COURSE - HISTOLOGY LAB: Protective epithelium - Common courses
Week 2: THEORETICAL Mitosis and meiosis - Connective tissue: definition, intercellular substance and fibrils - Cell cycle and control - Intravenous Intervention PRACTICE. - Connective tissue: Types and cells - Protein repair mechanisms - Cell cycle and control - Cell aging and death, apoptosis/autophagy - Calculation of joint forces - Structure-function relationship in biomolecules - READING ARTICLES - MEDICAL BIOLOGY LAB: Structural and numerical chromosome abnormalities - HISTOLOGY LAB: Glandular epithelium - Common Courses
Week 3: THEORETICAL The concept of elasticity and elastic properties in biological tissues - Cancer genetics - Health policy and organization in health - Intravenous intervention - EVALUATION - Basic Health Indicators - Cartilage and bone tissue histology - DNA and RNA technologies - Protein technologies - Bone and bone formation - READING ARTICLES - HISTOLOGY LAB. : Connective tissue - Common Courses
Week 4: THEORETICAL Getting to know the society - Epithelial tissue biochemistry - DNA and RNA technologies - Joints and synovial membranes Adipose tissue biochemistry - Skin histology - Common Courses - Formative Exam
Week 5: THEORETICAL Blood Tissue Biochemistry - Basic principles of imaging - Connective tissue biochemistry - Discussion: BIOCHEMISTRY - MEDICAL BIOLOGY LAB. : Applications of nucleic acid technologies -1 - MEDICAL BIOLOGY LAB. : Applications of nucleic acid technologies -2 - MEDICAL BIOLOGY LAB. : Applications of nucleic acid
technologies -3 - MEDICAL BIOLOGY LAB. : Applications of nucleic acid technologies -4 - HISTOLOGY LAB: Skin histology - READING ARTICLES - Common Courses
Week 6: THEORETICAL MEDICAL BIOLOGY LAB. MAKER-UP - HISTOLOGY LAB. MAKE-UP - MED104 END OF BOARD THEORETICAL EXAM - MED104 END OF BOARD PRACTICAL EXAM HISTOLOGY - MED104 END OF BOARD PRACTICAL EXAM - MEDICAL BIOLOGY - Common Courses
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• Theoretical exam: 79 %
• Laboratory: 19 %
• Practical: 2 %