TIP203

School of Medicine \ Medicine

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8

Compulsory

Turkish

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Bachelor's and Master's Degrees

This course examines the components of the digestive system, their macroscopic and microscopic structures, the mechanisms of digestion, the biochemical destruction of macromolecules taken with nutrition and their processing within the cell, the regulation of the digestive system and digestive mechanisms, the definition of metabolism, the regulation of metabolism, hormonal control mechanisms important in the regulation of metabolism, and the factors that change/affect metabolism.

Lehninger Principles of Biochemistry, 6th Edition, D. L. Nelson, M. M. Cox. WH Freeman and Company, 2013.
Harper's Illustrated Biochemistry, 29th Edition, R. K. Murray, D. A. Bender, K. M. Botham, P. J. Kennelly, V. W. Rodwell, P. A. Weil. McGraw Hill & Lange, 2012.
Clinically Oriented Anatomy, 7th Edition, K. L. Moore, A. M. R. Agur, A. F. Dalley. Lippincott Williams & Wilkins, 2013
İnsan Anatomisi Atlası, 5. Basım, F. H. Netter (Çev. Ed. : M. Cumhur). Nobel Tıp Kitabevi, 2011.
Bern&Levy Physiology, 6th Edition (Updated) BM Koeppen, BA Stanton, Mosby Elsevier, 2010
Vander's Human Physiology: The Mechanisms of Body Function 13 edition E Widmaier, H Raff , K Strang McGraw-Hill Education; (March 22, 2013)
Junqueira’s basic histology, 13th edition, AL Mescher, McGraw-Hill Education,2013

This course teaches the structural (anatomical, histological) and functional (physiological) features of the digestive system's organs and the functioning and control of metabolism.

1. Recognizes the structures of the digestive system components and shows them on models and cadavers.
2. Lists the functions of the digestive system components.
3. Explains the general mechanisms in the digestion of food.
4. Defines the characteristics of digestion in the mouth, stomach and small intestine.
5. Explains the role of exocrine secretions of the liver, gallbladder and pancreas in digestion.
6. Lists the absorption mechanisms.
7. Defines the molecular components of protein, amino acid, lipid, lipoprotein, carbohydrate and nucleotide metabolisms.
8. Explains the mechanisms and factors effective in the control and regulation of metabolism.
9. Uses automatic pipette and spectrophotometer.
10. Measures the levels of fructosamine, total protein and lipid peroxidation in healthy and diabetic human serum.
11. Measures the basal metabolic rate
12. Applies surgical sutures on a model
13. Applies a nasogastric tube on a model

Week 1: Digestion and absorption of nutrients, Introduction to digestive PHYSIOLOGY, oral digestion and swallowing, Carbohydrate metabolism and control, Oral Anatomy, HISTOLOGY of the upper digestive system, Common lessons, Simple skin suture (suture), skin suture removal, wound care
Week 2: Abdominal part of the esophagus and stomach, Duodenum, Digestion in the stomach, Jejunum and ileum, Large intestine, Pancreas and spleen, Arteries and nerves of the digestive tract, Liver and bile ducts, External secretions of the pancreas, Common lessons, Simple skin suture (suture), skin suture removal, wound care practice, Lab: Determination of fructosamine in serum, LAB: Upper digestive system histology
Week 3: Portal system, Lipid and lipoprotein metabolism, Lower digestive system histology, Nasogastric tube placement, Histology of the liver, bile ducts, gall bladder and pancreas, Peritoneum, omentum minus, majus and bursa omentalis, Amino acid and protein metabolism, Posterior abdominal wall and its major vessels and nerves, Liver functions and the role of bile in digestion, Nucleotide metabolism, Common Courses, Nasogastric tube placement practice, LAB: Mouth Anatomy, LAB: Stomach, omentum minus, majus and bursa omentalis, LAB: Lower digestive system histology
Week 4: Porphyrins and bile pigments, Digestion and absorption in the small and large intestines, Anterior abdominal wall Anatomy, inguinal canal, Amino acid and protein metabolism, Clinical anatomy, Cross-sectional anatomy, Large intestine motility and gastrointestinal hormones, Common Courses, Nasogastric tube placement evaluation, LAB: Liver, bile ducts, gallbladder and pancreas histology, Lab: Serum protein assay, LAB: Liver, bile ducts, pancreas and spleen, LAB: Posterior abdominal wall, large vessels and nerves in the posterior abdominal wall, LAB: Anatomy of the anterior abdominal wall and inguinal canal
Week 5: Detoxification mechanisms, Mineral metabolism, Development and anomalies of the digestive system, Case discussion, Common subjects, LAB: Physiology of the digestive system, LAB: Serum lipid peroxidation assay, Compensatory HISTOLOGY/ANATOMY/PHYSIOLOGY
Week 6: Common Courses, 203 FINAL BOARD EXAM THEORETICAL, Evaluation of theoretical exam answers, FINAL BOARD EXAM PRACTICAL ANATOMY/HISTOLOGY/PHYSIOLOGY
Week 7: -
Week 8: -
Week 9: -
Week 10: -
Week 11: -
Week 12: -

• Theoretical exam: 72 %
• Laboratory: 23 %
• Practical: 5 %