School of Medicine \ Medicine
Course Credit
ECTS Credit
Course Type
Instructional Language
Programs that can take the course
Bachelor's and Master's Degrees
This course examines changes in various metabolic processes, the structure and functioning of the immune system, cell injury, the inflammatory process that is the basic mechanism of most diseases and the regeneration and repair processes of diseased tissue, clinical pathologies, autonomic nervous system pharmacology, and statistical tests that make it possible to evaluate existing data in line with a hypothesis.
Textbook and / or References
Lehninger Principles of Biochemistry, 8th Edition, DL. Nelson, MM. Cox. WH Freeman
and Company 2021.
Harper's Illustrated Biochemistry, 29th Edition, McGraw Hill Lange, 2012.
Molecular Biology of the Cell, 5th Ed. , Garland Science, Taylor & Francis, 2008.
Thompson & Thompson Genetics in Medicine, 7th Edition, R. L. Nussbaum, R. R.
McInnes, H. F. Willard. Saunders, 2007.
Akılcı Tedavi Yönünden Tıbbi Farmakoloji 1-2, S. O. Kayaalp, Pelikan Tıp K. , 2024. Basic and Clinical Pharmacology, 16th Edition, B. Katzung and A. Trevor, Lange-
McGraw-Hill Medical, 2023
Rubin's Pathology: Clinicopathologic Foundations of Medicine, 7th Ediition,
D. S. Strayer, Wolters Kluwer, 2014.
Robbins Temel Patoloji, Çeviri Ed. S. Tuzlalı, M. Güllüoğlu, U. Çevikbaş, Nobel Tıp
Kitabevi 2014.
Lippincott İmmünoloji, , Çeviri Ed. S. Tuzlalı,G. Deniz,G. Erten, Y. Camcıoğlu, Nobel Tıp
Kitabevi 2014.
Cellular and Molecular Immunology, 8th Edition, AK Abbas, AHH Lichtman, Saunders,
2014.
Within the scope of this course board; aims to teach the concepts of being healthy and disease, the basic mechanisms that play a role in the formation of pathologies, the biological response and healing mechanisms of the organism against damaging factors and the pharmacology of the autonomic nervous system.
1. Explains the basic mechanisms that play a role in the formation of pathologies
2. List the main metabolic disorders and define their molecular mechanisms
3. Defines the immune system-disease relationship
4. Describes the types of immunity and the functions of the structures in the immune system
5. Lists the general characteristics of microorganisms
6. Defines the disease-causing mechanisms of microorganisms
7. Defines the autonomic nervous system and drugs that act on this system.
8. Explains the physiological effects of exercise and environmental conditions
9. Describes hypothesis tests and how they are applied
10. Uses a microscope by its technique
11. Stains a preparation by its technique
12. Cultivates in place of the medium
13. Performs latex agglutination tests
14. Measures and interprets physiological parameters in the exercise model.
15. Performs hypothesis tests using the SPSS program
Week 1: Lipid metabolism disorders, Edema, congestion, thrombosis, Research Planning: Sample size and Power, Introduction to Immunology and Structure of the Immune System, Environmental physiology, Introduction to autonomic nervous system pharmacology, Amino acid and protein metabolism disorders, Microbiota-Microorganism-Host Relationship, Common courses,
Week 2: Innate Immunity, Antigen Processing and Presentation, Antigens, Graph types, graph that best represents the data, sympathomimetic and sympatholytic drugs, Genetic diseases, Acquired Immunity and Antigen Recognition, Common courses, LAB: Exercise Physiology
Week 3: Parasympathomimetic and parasympatholytic drugs, Pharmacology of vitamins, Cellular Immunity, Innate and acquired immunity, DNA repair mechanisms and disorders, Hypersensitivity reactions, Mechanisms of Action of Cellular Immunity, Research Planning: Experimental research types, Health Statistics: Hospital Disease Birth and Death
statistics, Common courses, LAB: MICROBIOTAS
Week 4: Autoimmunity and Autoimmune diseases, Antigen Antibody Relations and Serological Tests, Active/Passive Immunization, Humoral Immunity, Tissue Rejection, Immunodeficiency Syndromes and Amyloidosis, Mechanisms of Action of Humoral Immunity, Common courses, Formative exam, LABORATORY COMPENSATION Microbiology/Physiology/Pathology
Week 5: 206 END OF BOARD EXAM THEORETICAL, Evaluation of theoretical exam answers, 206 END OF BOARD EXAM BIOSTATISTICS
Week 6: Theoretical: Genetic diseases, vitamin metabolism disorders, humoral immunity, active, passive immunity, immune tolerance, autoimmunity, side effects of drugs,
Practical: Serological tests Week 6: Theoretical: Tumor definition, classification, immunity, carcinogenesis, childhood age tumors, autocoids, serotonin, histamine, health statistics
Practical: Benign and malignant tumors
Week 7: -
Week 8: -
Week 9: -
Week 10: -
Week 11: -
Week 12: -
Tentative Assesment Methods
• Theoretical exam: 82 %
• Laboratory: 18 %
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