TIP208

School of Medicine \ Medicine

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8

Compulsory

Turkish

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Bachelor's and Master’s

This course examines the structures of the glands that make up the endocrine system, the hormones they secrete, the processes of hormone production and secretion, the control of secretion, and the effects of hormones. It includes topics such as the concept of a drug, mechanisms of action, factors that change its effect, drug forms and routes of administration, how new drugs are developed, pharmacokinetics, and dose-concentration-effect relationships.

"Lehninger Principles of Biochemistry, 8th Edition, D. L. Nelson, M. M. Cox. WH Freeman
and Company 2021.
Molecular Biology of the Cell, 6th Edition, B. Alberts, A. Johnson, J. Lewis, D. Morgan,
M. Raff, K. Roberts, P. Walter. Garland Science, Taylor Francis 2015.
Gray's Anatomi (öğrenciler için). AW Vogl, AWM. Mitchell, RL. Drake. Çeviri Ed: Beliz
Taşçıoğlu, Meserret Cumhur, Selçuk Tunalı. Nobel Tıp Kitabevi 2018.
Arıncı - Anatomi 1-2. Alaittin Elhan, Kaplan Arıncı. Güneş Tıp Kitabevi 2020.
Netter İnsan Anatomisi Atlası 7. Baskı. Frank H. Netter, Çeviri Ed: Meserret Cumhur.
Güneş Tıp Kitabevi, 2020.
An Atlas of Histology, S. X. Zhang 1999. DOI: https://doi. org/10. 1007/978-0-387-
21760-4
A Text and Atlas: With Correlated Cell and Molecular Biology,8th Ed. W. Pawlina, M. H.
Ross 2018. ISBN-13: 978-1496383426
Junqueira's Basic Histology, Text and Atlas, 16th Ed. , A. L. Mescher 2021.
Akılcı Tedavi Yönünden Tıbbi Farmakoloji 1-2, S. O. Kayaalp, Pelikan Tıp K. , 2024. Basic and Clinical Pharmacology, 16th Edition, B. Katzung and A. Trevor, Lange-
McGraw-Hill Medical, 2023
Robbins Temel Patoloji, Çeviri Ed. S. Tuzlalı,, M. Güllüoğlu, U. Çevikbaş, Nobel Tıp
Kitabevi 2014.
Lippincott İmmünoloji, Çeviri Ed. S. Tuzlalı, G. Deniz, G. Erten, Y. Camcıoğlu, Nobel Tıp
Kitabevi 2014.
Guyton and Hall textbook of Medical Physiology 14th, Elsevier 2020.
Vander's Human Physiology: The Mechanisms of Body Function 15 edition E
Widmaier,H Raff, K Strang McGraw-Hill Education; 2019. "

The purpose of this course is to teach the structural and functional properties of the endocrine system, regulatory mechanisms, the concept of drugs and general pharmacology information.

1. Lists the general characteristics of the endocrine system and hormones
2. Knows the names and locations of endocrine glands
3. Defines the structures and features of endocrine glands
4. Lists the hormones secreted by endocrine glands
5. Defines the factors affecting hormone secretion
6. Lists the biochemical mechanisms of action of hormones
7. Classifies hormones according to their structures, locations and functions
8. Defines the effects of hormones on physiology and metabolism
9. Defines cellular injury, cellular adaptation, necrosis and apoptosis
10. Lists the basic concepts of medical ethics
11. Defines ethical theories
12. Defines drugs, knows how they work and how they can change.
13. Knows how new drugs are developed and defines the pharmacokinetic properties of drugs
14. Defines ethical problems related to the beginning and end of life
15. Know the stages of moral development.
16. Shows anatomical structures in the endocrine system on models and cadavers
17. Recognizes tissues in the endocrine system microscopically
18. Defines microscopic features of cellular injury

Week 1: Hormones: General overview, Hypothalamus-pituitary functional relationship, Growth factors, Melatonin and erythropoietin, BIOCHEMISTRY and functions, Hypothalamus and pituitary hormones, Glandula thyroidea and glandula parathyroidea, Introduction to Pharmacology, Thyroid hormones, Suprarenal gland and thymus, Anterior pituitary hormones, Development and histology of pituitary, pineal, thyroid and parathyroid glands, Steroid hormones, Introduction to Medical Ethics, Introduction to Medical Ethics, Effects of thyroid hormones, Common courses,
Week 2: Catecholamines, Biosynthesis and activities of eicosanoids, Development and histology of adrenal gland, endocrine pancreas and general neuroendocrine system, Introduction to Pathology, Technique and Function, Effects of adrenal gland hormones, Ethical Theories 1-Utilitarian and Principlist Approach, Cellular Injury, Ethical Theories 2- Virtue Ethics and Deontological Approach, Pharmaceutical Forms and Administration Routes of Drugs, Cellular Adaptation, Hormones Affecting Calcium Homeostasis and Bone Metabolism, Mechanisms of Action of Drugs and Factors Changing the Effect of Drugs, Common courses, LAB: Endocrine system, LAB: Glandula thyroidea and glandula parathyroidea, LAB: Glandula suprarenalis and thymus, LAB: Thyroid physiology
Week 3: Clinical Anatomy, Calcium and Phosphorus Metabolism, Other Ethical Theories and Application of Ethical Theories, Energy Metabolism, Hunger, Satiety and Obesity, Necrosis Apoptosis, Regulation of Body Temperature, Clinical evaluation of new drugs, Membrane penetration of drugs and absorption, Hormonal Control of Metabolism and Obesity, Adipose Tissue, Pancreatic and Gastrointestinal Hormones, Common courses
Week 4: Moral Development Stages, Ethical issues related to the beginning and end of life, Distribution, Metabolism and Excretion of drugs, Dose-Concentration-Effect relationship, Drug-Receptor relationship, Pharmacogenetics Common courses, Lab: Cellular Injury - Pathology, LAB: Metabolic Rate Determination, Formative exam, COMPENSATORY ANATOMY/HISTOLOGY/PHYSIOLOGY
Week 5: Common courses, END OF 208 BOARDS EXAM THEORETICAL, Evaluation of theoretical exam answers, 208 FINAL BOARD EXAM PRACTICAL ANATOMY/HISTOLOGY/PHYSIOLOGY
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• Theoretical exam: 98 %
• Laboratory: 2 %